by Z Hardcastle · 1998 · Cited by 480 — epithelial) signalling in early tooth development.. Ectopic application of Shh protein to mandibular mesenchyme induced the expression of Ptc and Gli1.
by Z Hardcastle · 1998 · Cited by 480 — This suggests that Shh is involved in both lateral (epithelial-mesenchymal) and planar (epithelial-epithelial) signalling in early tooth ...
Nov 1, 2015 — During the early stages of tooth development the SHH signalling is closely controlled along the oral axis of the first branchial arch.. Hence.
by R Maas · 1997 · Cited by 304 — The important role that Msx genes play in tooth development is exemplified ... Bone morphogenetic proteins and a signalling pathway that controls patterning ...
by M Seppala · Cited by 37 — The repeated expression of Shh in epithelium of the developing tooth prompted early studies investigating the role of this signal pathway ...
by FD Nunes · 2007 · Cited by 6 — Localization of Bmp-4, Shh and Wnt-5a transcripts during early mice tooth ... of the Shh signaling pathway during mice dental tissues development using Shh ...
by X Hu · 2013 · Cited by 33 — In the mouse, Shh signaling pathway has been shown previously to exert pivotal roles at various steps during tooth development.
by I Miletich · 2003 · Cited by 199 — During their early development, tooth germs exhibit many ... defects in the Shh signalling pathway.. Despite Gli3 mutants displaying no obvious tooth ...
by J He · 2021 · Cited by 1 — Mammalian tooth crown formation has long served as a model for ... Wnt signaling pathway was the top pathway affected by Lhx6 loss (S6B Fig) ...
Apr 14, 2021 — This study aimed to elucidate the role of the Sonic hedgehog (Shh)–Patched (Ptch)–Gli signaling pathway in maintaining dental epithelial and ...
by AMC Couzens · 2021 — A hallmark of early dental evolution in many placental lineages was a ... that manipulating a range of signaling pathways (sonic hedgehog, ...
by I Thesleff · 1997 · Cited by 727 — Of the hedgehog family, sonic hedgehog (Shh) is expressed in dental epithelium at several stages starting in the early epithelial thickenings, then reappears in ...
Feb 19, 2020 — Shh activates the whole signaling pathway via interacting with its specific receptor, Ptc/Smo protein complex.. During the early tooth ...
by J Li · 2015 · Cited by 99 — BMP-SHH Signaling Network Controls Epithelial.. Stem Cell Fate via Regulation of Its Niche in the.
Developing Tooth. sore teeth sick
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by T Sagai · 2017 · Cited by 15 — The WNT and BMP signaling pathways are known as two major mediators of the interaction during early tooth development.
by W Yu · 2017 — ... the sonic hedgehog (Shh) signaling pathway by regulating the expression of Shh in the dental epithelial signaling center during early tooth development.
early stages of both dentine and enamel secretion begin- ning to occur (Figure 1).. ... The Shh signalling pathway in tooth development: defects in Gli-2.
by M Varjosalo · 2008 · Cited by 1265 — (B) The central conserved components of the Hh signaling pathway and their role in ... For example, Shh and Ihh act together in early embryonic development, ...
by A Hosoya · 2020 · Cited by 12 — Roles of Shh signaling during tooth development.. ... M.T. traduzione di teeth lady gaga
Hedgehog pathway gene expression during early development of the molar tooth root .... first aid for teeth injuries
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